This team at the University of Leeds used transgenic mice to study the impact of the Atp1a3 gene on epileptic like seizures. The mice that lacked this gene had the seizures and were cross bred with mice that had a double copy of the gene. The offspring of these mice were completely free of epilepsy. The mouse Atp1a3 gene is >99% identical to the human gene and encodes for a sodium-potassium pump. Epilepsy affects around 1 in every 200 people.
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