In this paper, the hydroxylation and dealkylation of cisapride in various in vitro systems is described. CYP3A is implicated as being the major enzyme involved in the N-dealkylation.
Monday, August 31, 2009
CYP3A Involved in Cisapride Metabolism
In this paper, the hydroxylation and dealkylation of cisapride in various in vitro systems is described. CYP3A is implicated as being the major enzyme involved in the N-dealkylation.
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