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Sunday, November 29, 2009

Mutations May Protect Against Infection


In this paper, a team of researchers from the NIH describe a potential new mechanism for cellular defense against viruses, bacteria, and oxidative stress that involves mutation of amino acids in proteins to methionines. They hypothesize that the reason is that the methionines protect against cellular damage cause by reactive oxygen species. I wonder why the residues are mutated to only methionine and not cysteine as well. Also, I would like government researchers to be forced to publish in freely available journals. We should not have to pay again just to read their research results - they already get $$ from us to conduct the research!

Anyway, the full paper is here...

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